Royal Air Force Typhoon jets have operated alongside French aircraft in a combined operation against an hidden munitions depot in Syrian territory operated by the IS group, per a report from the UK's MoD.
The site, identified by intelligence, was believed to be storing arms and explosives, the statement said, and was situated in hills just to the north of the historic site of Palmyra in Syria's central region.
"Our fighter planes utilized precision-guided Paveway IV munitions to target a several access tunnels down to the facility... preliminary assessments are that the target was engaged successfully," the MoD said.
There was no sign of any civilian casualties in the strike late on Saturday and each participating jet returned safely, the ministry further stated.
The Typhoon FGR4s were backed up by a Voyager tanker plane.
Daesh - alternatively referred to as the so-called Islamic State - imposed jihadist rule over parts of Iraq and Syria prior to its 2019 collapse.
"This strike underscores our UK leadership, and determination to operate in unison with our partners, to eradicate any resurgence of Daesh and their violent and radical beliefs in the Middle East," Britain's Defence Chief the minister said.
UK warplanes have performed patrols over Syrian airspace to "forestall any efforts to regroup" of the group following its routing at the Baghuz confrontation in the year 2019, the MoD reported.
"I extend gratitude to every member of our armed forces participating in this operation for their expertise and their courage," he said. "Including them were thousands of British personnel on duty over Christmas and New Year. This mission, to take out terrorist threats who threaten our security, shows how British military are always on standby, throughout the year, keeping Britain secure within its borders and powerful internationally."
In December, the United States armed forces executed what it termed a "major assault" against Daesh sites in Syria, following an attack killed two US troops and a civilian interpreter in the Palmyra area.
The U.N. estimates Daesh still has between 5,000 and 7,000 fighters in Syria and Iraq.